C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells
Abstract Background Triptolide is a structurally unique diterpene triepoxide with potent antitumor activity.However,the effect and mechanism of triptolide on hepatocellular carcinoma (HCC) is not well studied.Methods Cells were treated with triptolide, and the anti-HCC activity of triptolide was evaluated using flow cytometry, western blot, and xen