C-MYC-DEPENDENT REPRESSION OF TWO ONCOGENIC MIRNA CLUSTERS CONTRIBUTES TO TRIPTOLIDE-INDUCED CELL DEATH IN HEPATOCELLULAR CARCINOMA CELLS

C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells

Abstract Background Triptolide is a structurally unique diterpene triepoxide with potent antitumor activity.However,the effect and mechanism of triptolide on hepatocellular carcinoma (HCC) is not well studied.Methods Cells were treated with triptolide, and the anti-HCC activity of triptolide was evaluated using flow cytometry, western blot, and xen

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CHARACTERISTICS OF DISABILITY MANAGER AS A PROFESSIONAL EDUCATOR

The paper has the aim to assess the role that the figure of the professional educator is able to perform in a system that handles disability in performant and educational way.This implies the need to insert the educator Slings in a management model capable of developing a new cultural approach aimed to the inclusion and exploitation of disabled peo

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PROBLEMATIKA DAN PROSPEK WAKAF PRODUKTIF DI INDONESIA

This paper aims to describe and analyze the problems and prospects of endowments (perwakafan) in Indonesia, mainly related to the enactment of Law No.40 of 2004 on Waqf.An analysis of the problems focused on management of waqf properties by waqf institutions that are still traditional and far from productive orientation.The problems on waqf managem

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Mapping Electoral Districts and Seat Allocation for the 2024 Elections: A Case Study of Boyolali District Election Commission (KPU)

This article aims to analyze the application of the seven principles of electoral district structuring and seat allocation in the 2024 elections.The problem focuses on Electoral District Arrangement and Seat Allocation in Boyolali Regency which is experiencing the expansion of sub-district areas, from 19 sub-districts to 22 sub-districts.To approac

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